Chromosomal rearrangements and protein globularity changes inMycobacterium tuberculosisisolates from cerebrospinal fluid
نویسندگان
چکیده
منابع مشابه
Chromosomal rearrangements and protein globularity changes in Mycobacterium tuberculosis isolates from cerebrospinal fluid
BACKGROUND Meningitis is a major cause of mortality in tuberculosis (TB). It is not clear what factors promote central nervous system invasion and pathology but it has been reported that certain strains of Mycobacterium tuberculosis (Mtb) might have genetic traits associated with neurotropism. METHODS In this study, we generated whole genome sequences of eight clinical strains of Mtb that wer...
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Background and Objective: Bacterial meningitis is an important cause of mortality and long-term neural morbidity. Immediate diagnosis and treatment are necessary in appropriate time. This study was designed in Afzalipour Hospital in Kerman to evaluate meningitis causes, frequency and CSF laboratory changes. Patients and Methods: In this retrograde descriptive study from September 2003 to Se...
متن کاملRearrangements and chromosomal evolution.
Comparisons of the genome sequences of related species suggests varying patterns of chromosomal rearrangements in different evolutionary lineages. In this review, I focus on the quantitative characterization of rearrangement processes and discuss specific inventories that have been compiled to date. Of particular interest are the statistical distribution of the lengths of inverted or locally tr...
متن کاملChromosomal rearrangements and speciation.
Several authors have proposed that speciation frequently occurs when a population becomes fixed for one or more chromosomal rearrangements that reduce fitness when they are heterozygous. This hypothesis has little theoretical support because mutations that cause a large reduction in fitness can be fixed through drift only in small, inbred populations. Moreover, the effects of chromosomal rearra...
متن کاملEstimation of cerebrospinal fluid protein.
Three turbidometric methods and one method using ultraviolet spectrophotometry for estimating total cerebrospinal fluid protein have been examined. The necessity for preliminary dialysis renders the ultraviolet method unsuitable for routine use. The turbidometric method of Meulemans (1960) using a sulphosalicylic acid-sodium sulphate precipitating fluid is better than a method using sulphosalic...
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ژورنال
عنوان ژورنال: PeerJ
سال: 2016
ISSN: 2167-8359
DOI: 10.7717/peerj.2484